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In this tutorial, FABIAN-variant is used to analyze variants from a whole genome sequencing (WGS) run using transcription factor flexible models (TFFMs).
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26.05.2022 · The search can be restricted to variants in the vicinity of candidate genes. FABIAN-variant is available freely at https://www.genecascade.org/ ...
FABIAN is a web-based application that uses TFFMs and PWMs to predict the degree to which DNA variants are likely to disrupt (or create) the binding sites of ...
05.07.2022 · The search can be restricted to variants in the vicinity of candidate genes. FABIAN-variant is available freely at https://www.genecascade.org/ ...
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09.06.2022 · However, the interaction between this SNP and our candidate gene PTBP2 was not significant (p value = 0.85) and FABIAN did not imply an effect ...
Direct comparison of binding models generated by different methods. Depicted are AUC scores for TFs stored in both JASPAR (manually collected curated ...
01.07.2022 · This is the 20th edition of the Nucleic Acids Research Web Server Issue. Under normal circumstances, this would be an opportunity to ...
17.10.2016 · Astonishing progress has been made in the molecular biology of neurochemistry during the 60 years since this journal debuted. Many of the gains ...